Peter Attia discusses metformin in the context of its use for improving metabolic health and its potential geroprotective benefits. Here are some key points he makes with timestamps:

1. Metformin as a pharmacological option for metabolic health (Timestamp: 00:03:50.000):
- Attia talks about the different pharmacological options that can be used to improve metabolic health, including SGLT2 inhibitors, GLP-1, and others, with metformin being one of these drugs.

2. Comparison of metformin with SGLT2 inhibitors (Timestamp: 00:17:31.000):
- He compares the weight loss effects of metformin to those of canagliflozin, a type of SGLT2 inhibitor, suggesting that he believes metformin might be associated with slightly more weight loss than monotherapy with SGLT2 inhibitors, although he invites verification of this claim.

3. Metformin's popularity and excitement beyond diabetes (Timestamp: 00:20:43.000):
- Attia explains that while metformin is a well-known early intervention for type 2 diabetes, the excitement around it is not solely for its glycemic control benefits. He implies there are other reasons why people are interested in metformin and intend to discuss them further.

4. Metformin's natural origins (Timestamp: 00:14:13.000):
- He mentions that metformin is pretty close to the original molecule discovered in the lilac lilies, indicating its natural origin.

5. Brief mention in the context of glucose-lowering strategies (Timestamp: 00:10:08.000):
- While discussing strategies for lowering glucose levels, Attia includes metformin as one of the strategies, alongside others like increasing insulin sensitivity or administering insulin itself.

These points provide a summary of what Attia says about metformin in the provided context.

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